The latest technological advance in the field of fractional lasers is demonstrated in a novel fractional device: Affirm with Multiplex technology (Cynosure, Westford, Massachusetts), a combination Nd:YAG laser emitting 1320- and 1440-nm wavelengths in sequential 3-millisecond pulses composed of 1000 microbeams per 10-mm spot. The 1440-nm wavelength exerts a resurfacing effect and acts more superficially, targeting rhytids and pigmentation. The 1320-nm wavelength targets deeper tissues, stimulating neocollagenesis and thereby improving skin laxity.