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October 20, 2008

Multiple Collections of Soft Bluish Nodules on the Body—Quiz Case

Arch Dermatol. 2008;144(10):1383-1388. doi:10.1001/archderm.144.10.1383-c

A 40-year-old man presented with several bluish nodules on his body. He stated that the first lesion had arisen on his left lower extremity years earlier, possibly during childhood, and other lesions had eventually appeared on his trunk, arms, and legs. Physical examination revealed several collections of soft, compressible, bluish, 5- to 8-mm nodules on the trunk, right upper hip region, and all 4 extremities (Figure 1). The patient denied any associated pain or pruritus, but the lesions were tender on deep palpation. The findings of the rest of his physical examination were unremarkable. His family history was significant for similar lesions on his 2 sons and his father. He denied any history of gastrointestinal bleeding, and the results of a colonoscopy were noncontributory. A biopsy specimen was obtained from one of the lesions on his right arm and sent for histopathologic examination (Figure 2 and Figure 3).

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