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October 20, 2008

Multiple Collections of Soft Bluish Nodules on the Body—Diagnosis

Arch Dermatol. 2008;144(10):1383-1388. doi:10.1001/archderm.144.10.1383-g

Histopathologic study of the biopsy specimen revealed an ill-defined, nonencapsulated lesion within the reticular dermis and subcutaneous tissue. The lesion was composed of thick- and thin-walled blood vessels, some of which had a single or double layer of glomus cells.

Glomangioma is a tumor of neuromyoarterial glomus that is composed of vascular channels surrounded by proliferating glomus cells and nerve fibers.1,2 Glomus tumors are rare. Some are present at birth; they rarely appear during infancy, but the incidence increases from the age of 7 years onward. Multiple tumors are 10 times more common in children than in adults. The solitary tumor is a pink or purple nodule varying in size from 1 to 20 mm; it is conspicuously painful. The common sites are the extremities. Subungual tumors are very painful. Multiple tumors, which are larger and usually dark blue, are situated deepin the dermis. They are less restricted to the extremities, may be widely scattered, and are not usually painful.1,2

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