We describe 3 cases of Reed nevi in childhood, with dermoscopic sequential changes over a 6- to 15-month period. Case 1 involved an 8-year-old girl with a pigmented lesion located on her right knee (Figure 1A and B), with follow-up examinations at 4 (Figure 1C) and 15 (Figure 1D) months. Case 2 involved a 7-year-old boy with a pigmented lesion on his left leg (Figure 2A and B), with follow-up examinations at 4 (Figure 2C) and 7 (Figure 2D) months. Case 3 involved a 15-year-old boy with a pigmented lesion located on his left arm (Figure 3A and B), with a follow-up examination at 6 months (Figure 3C).