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October 2010

A Tooth for an Eye: Cicatricial Pemphigoid and the Osteo-Odonto-Keratoprosthesis

Author Affiliations

Author Affiliations: Dermatological Sciences, The University of Manchester, Manchester Academic Health Science Centre, Manchester, England (Drs Langan, Ogden, and Griffiths); and Sussex Eye Hospital, Brighton and Sussex Medical School, Brighton, England (Dr Liu).

Arch Dermatol. 2010;146(10):1188-1189. doi:10.1001/archdermatol.2010.277

A 67-year-old woman with biopsy-proven cicatricial pemphigoid had bilateral cicatricial entropion and trichiasis leading to blindness in the right eye and severe visual impairment in the left eye. This occurred despite treatment that included methylprednisolone, prednisolone, methotrexate, cyclosporine, dapsone, mycophenolate mofetil, intravenous immunoglobulins, and plasma exchange. In the hope of rescuing her sight, she was referred for an osteo-odonto-keratoprosthesis (OOKP) for her right eye.

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