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December 2010

Multiple Myeloma–Associated Amyloidosis Presenting With Acrolocalized Acquired Cutis Laxa

Author Affiliations

Author Affiliations: Departments of Dermatology (Drs Ferrándiz-Pulido, Serra, Repiso, and Garcia-Patos) and Pathology (Dr Ferrer), Hospital Universitario Vall d’Hebron, Universitat Autonoma de Barcelona, Barcelona, Spain; and Department of Dermatology, Hospital Verge de la Cinta de Tortosa, Tarragona, Spain (Dr Bel).

Arch Dermatol. 2010;146(12):1435-1437. doi:10.1001/archdermatol.2010.365

Cutis laxa (CL) syndrome is an inherited or acquired disorder due to abnormal production or destruction of dermal elastic fibers. Acquired forms may be localized or generalized and frequently are related to preceding inflammatory dermatoses or monoclonal gammopathies. Acral CL is an exceptional form of acquired localized CL that may indicate an underlying multiple myeloma.1-6