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Evidence-Based Dermatology: Research Commentary
April 11, 2011

A Randomized Controlled Trial of the Addition of Mycophenolate Mofetil or Placebo to Oral Corticosteroids in the Treatment of Pemphigus Vulgaris Fails to Demonstrate a Significant Difference in the Primary Outcome or Quality of Life

Arch Dermatol. 2011;147(4):489-491. doi:10.1001/archdermatol.2011.56

Beissert S, Mimouni D, Kanwar AJ, Solomons N, Kalia V, Anhalt GJ

J Invest Dermatol. 2010;130(8):2041-2048.

Question: In outpatients with mild or moderate pemphigus vulgaris, does treatment with prednisone and mycophenolate mofetil increase the portion of patients who respond to treatment compared with those who received treatment with prednisone and placebo?

Design: Investigator and patient masked, randomized-controlled trial.