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April 2011

Pigmented Basal Cell Carcinomas 15 Years After Orbital Radiation Therapy for Graves Ophthalmopathy

Author Affiliations

Author Affiliations: Departments of Dermatology, Venereology, and Allergology (Drs Haenssle, Buhl, Haas, Holzkamp, Emmert, and Schön), and Radiotherapy and Radiooncology (Dr Richter), Georg August University Göttingen, Göttingen, Germany.

Arch Dermatol. 2011;147(4):511-512. doi:10.1001/archdermatol.2011.74

A 54-year-old man of Turkish descent and skin type III observed 2 progressing lesions at his right and left temporal scalp. Fifteen years earlier he had received cobalt-60 retrobulbar radiation therapy for Graves ophthalmopathy (GO) symptoms, including diplopia, eyelid retraction, and altered ocular motility. The clinical examination revealed 2 symmetrically distributed lesions of asymmetrical shape and gray-brown color (Figure 1A-D). The lesion at the right temple had a palpable patchlike appearance with a few scales, while the lesion at the left temple showed a central ulceration and branched pigmented streaks. Dermoscopy revealed diagnostic features of pigmented basal cell carcinoma (BCC) (Figure 1E and F).1 After complete excision, the diagnosis of 2 pigmented nodular BCCs was confirmed by histopathologic analysis (Figure 2).

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