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February 2011

Congenital Microcystic Adnexal Carcinoma

Author Affiliations

Author Affiliations: Departments of Dermatology (Ms Fu and Drs Clark and Bruckner), Surgery (Dr Lorenz), and Pediatrics (Dr Bruckner), Stanford University School of Medicine, Stanford, California; and Palo Alto Medical Foundation, Mountain View, California (Dr Clark).

Arch Dermatol. 2011;147(2):256-257. doi:10.1001/archdermatol.2010.440

Microcystic adnexal carcinoma (MAC) also known as sclerosing sweat duct carcinoma, is a rare cutaneous neoplasm with ductal and follicular components that is locally aggressive.1,2 It usually occurs in adults, most frequently on the head and neck.2 The diagnosis is made histopathologically, and the differential diagnosis includes syringoma and desmoplastic trichoepithelioma. We describe herein the first congenital MAC to our knowledge.