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June 1999

Fluorescence-Activated Cell Sorter Analysis in Patients With Cutaneous Lupus Erythematosus

Author Affiliations

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Arch Dermatol. 1999;135(6):720-721. doi:10-1001/pubs.Arch Dermatol.-ISSN-0003-987x-135-6-dlt0699

Lymphocytopenia is a well-known feature of patients with systemic lupus eythematosus (SLE).1,2 Less data are available concerning whether patients with cutaneous LE also have low lymphocyte counts.3 We present data on 73 patients with LE that concern lymphocyte counts in the peripheral blood, including T-cell subsets as detected by fluorescence-activated cell sorter analysis. We emphasize that it is necessary to measure lymphocyte subpopulations, eg, helper T (CD3+CD4+ cells) and both suppressor and cytotoxic T cells (CD3+CD8+ cells) in the diagnosis and follow-up of all types of LE.

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