In Southeast Asia, there have been few studies on the emergence of antibiotic-resistant strains of Propionibacterium acnes. This preliminary study describes the effects of short courses of antibiotics on minimum inhibitory concentrations (MICs) of P acnes.
We compared the MICs of P acnes with some commonly used antibiotics in 2 groups of patients with acne vulgaris: one (group A) that had received no prior antibiotic treatment and the second (group B) that had received a course of systemic antibiotics, ranging from 6 to 18 weeks during the past 6 months.