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August 1999

Diffuse Painless Ulcerations

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Arch Dermatol. 1999;135(8):983-b-988. doi:10-1001/pubs.Arch Dermatol.-ISSN-0003-987x-135-8-dof0899

A punch biopsy specimen from the border of an ulcer revealed a patchy infiltrate of foamy histiocytes and scattered lymphocytes in the dermis and subcutaneous fat, tending to be clustered around blood vessels. Large number of acid-fast bacilli were present in the Ziehl-Neelsen stain of the specimen. Foamy histiocytes and acid-fast bacilli were also noted in the wall of the medium-sized arteries, with narrowing of the vessel lumen. No nuclear dust was observed. Slit-skin smears showed single and clustered acid-fast bacilli.

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