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November 1999

Erythroderma in a Patient With Arthralgias, Uveitis, and Dyspnea

Arch Dermatol. 1999;135(11):1409-c-1414. doi:10-1001/pubs.Arch Dermatol.-ISSN-0003-987x-135-11-dof9021

A granulomatous dermal infiltrate consisting predominantly of histiocytes and multinucleated giant cells of Langhans and foreign body types, as well as lymphocytes and rare eosinophils, was evident on hematoxylin-eosin–stained sections. The granulomas were located in the upper half of the dermis and were focally periadnexal in distribution (Figure 2 and Figure 3). Special stains were negative for mycobacteria and fungal organisms. Polarizable material was not identified within the granulomas.