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Off-Center Fold
December 1999

Linear Warty Lesions in a Child

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Arch Dermatol. 1999;135(12):1543-b-1548. doi:10-1001/pubs.Arch Dermatol.-ISSN-0003-987x-135-12-dof9025

Hematoxylin-eosin–stained sections revealed irregular epidermal hyperplasia with a vertical column of parakeratotic cells, the so-called cornoid lamella. Beneath the cornoid lamella, the granular layer was decreased, and there were many dyskeratotic and vacuolated cells. There was a diffuse lymphohistiocytic infiltrate in the papillary dermis. The epidermis on either side of the cornoid lamella was orthokeratotic, with a thickened granular cell layer. These findings were consistent with porokeratosis. The patient was treated with topical fluorouracil, with some improvement.

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