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April 2001

Appropriate Controls Are Essential in Assessing the Relationship Between Circumcision and Penile Dermatoses

Arch Dermatol. 2001;137(4):503-504. doi:

In reply

I have seen Dr Anne Laumann's letter to the ARCHIVES regarding our article on circumcision and genital dermatoses.1 On behalf of all the authors, I would like to reply as follows.

First, Dr Laumann comments that the controls were older, on average, than the patients. Fortunately, there was considerable overlap, enabling us to present the odds ratios adjusted for 10-year age groups. These are the odds ratios expected in a hypothetical population, with age distribution similar to that of our cases. These adjusted odds ratios will not be affected by any pre– and/or post–"sexual revolution" or pre– and/or post–British Health Service contrast. Moreover, they were similar to the corresponding unadjusted odds ratios. Therefore, if there is a confounder, it is not age.

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