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February 2002

Familial Confluent and Reticulated Papillomatosis

Author Affiliations

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Arch Dermatol. 2002;138(2):276-277. doi:10.1001/archderm.138.2.266

While confluent and reticulated papillomatosis (CRP) was first described by Gougerot and Carteaud1 in 1927, its pathophysiology is still not understood. We report familial CRP in 2 brothers with characteristic clinical features. Ultrastructural and immunohistochemical findings in both cases suggest that familial CRP is related to abnormal keratinocyte differentiation.