A 49-year-old woman who had been diagnosed 7 months earlier as having Crohn disease presented with a 6-week history of multiple lesions on both legs. She had been treated with bacitracin ointment, without improvement. She had no history of trauma, and she denied having symptoms in association with the lesions. Her medical history was significant for cholelithiasis status postcholecystectomy 2 years earlier. Her medications at the time of presentation included oral dexamethasone (3 mg/d), oral mesalamine (3600 mg/d), oral lansoprazole (30 mg/d), oral citalopram (30 mg/d), oral multivitamins, and birth control pills.