The vulvar biopsy specimen revealed a noncaseating granulomatous lesion composed of epithelioid histiocytes and giant cells surrounded by a thin rim of lymphocytes. Also, there were Schistosoma ova surrounded by granulomatous inflammation. The Schistosoma ova showed a terminal spine characteristic of Schistosoma haematobium. Ziehl-Neelsen, periodic acid–Schiff, and Fite stains were negative for organisms. There was no evidence of schistosomiasis elsewhere in the body.
Vulvar Lesion in a 45-Year-Old Woman. Arch Dermatol. 2002;138(9):1245–1250. doi:10.1001/archderm.138.9.1245