Copyright 2002 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2002
The article titled "Tazarotene Cream for the Treatment of Facial Photodamage" in the December 2001 issue of the ARCHIVES1 is far removed from the standards of evidence-based medicine. There are missing data, numerical juggling, and selective reporting of data.
In the authors' summary, percentage success rates are based on "global response," a measure that involved the investigator's memory. At each visit, evaluators compared the subject's condition with their recall of the subject's appearance at baseline and scored this on a 7-point scale. Is it realistic to expect an investigator to remember what the subject's skin looked like 6 months ago?
Epstein E. Questionable Techniques for Evaluating Photodamage. Arch Dermatol. 2002;138(11):1515. doi:10.1001/archderm.138.11.1515
Customize your JAMA Network experience by selecting one or more topics from the list below.