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skINsight
July 2004

Dermoscopy of Melanocytic NeoplasmsCombined Blue Nevi

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Copyright 2004 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2004

Arch Dermatol. 2004;140(7):902. doi:10.1001/archderm.140.7.902

The lesions shown are from the cheek of an 18-year-old white man (Figure 1), and the cheek of an 8-year-oldwhite child (Figure 2) (size bar,5 mm). Both the lesions reveal a relatively similar pattern. Coloration is clearly two-tone with a brown overlying component and an underlying blue component.In the lesions shown, the brown and bluecomponents appear to have similar dimensions. Theoretically, combined blue nevi may result from a clone of cellsthat migrate and differentiate along 2 different pathways. Another possibility could include a field effect resulting in a secondary melanocytic proliferationin response to factors secreted from the primary population.

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