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Evidence-Based Dermatology: Research Commentary
September 2004

Melanoma Margins: The Importance and Need for More Evidence-Based Trials

Author Affiliations

Michael E.BigbyMDRosamariaCoronaDSc, MDDamianoAbeniMD, MPHAlexandra B.KimballMD, MPHMoysesSzkloMD, MPH, DrPHHywelWilliamsMSc, PhD, FRCP

Arch Dermatol. 2004;140(9):1148-1150. doi:10.1001/archderm.140.9.1148

Commentary on: Excision margins in high-risk malignant melanoma

Thomas JM, Newton-Bishop J, A'Hern R, et al, for the United Kingdom Melanoma Study Group, the British Association of Plastic Surgeons, and the Scottish Cancer Therapy Network

N Engl J Med. 2004;350:757-766.

Question: In patients with primary cutaneous melanoma 2 mm or thicker, is there a significant difference in recurrence and/or survival for excision with 1- vs 3-cm margins?

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