Efficacy of the 308-nm Excimer Laser in the Treatment of Mycosis Fungoides

Mycosis fungoides (MF) is an epidermotropic cutaneous CD4⁺ T-cell lymphoma. The accessibility of the lesions, along with the failures of studies to demonstrate prolonged survival using more aggressive systemic therapy, confirms that topical therapeutic modalities are the treatment of choice for localized MF.¹ The efficacy of phototherapy in the patch stage of MF has been well documented.² We conducted an open prospective study to assess the efficacy of treatment with the 308-nm excimer laser in localized MF.