[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Citations 0
Off-Center Fold
November 2004

A Pigmented Verrucous Plaque on the Cheek—Diagnosis

Author Affiliations

Copyright 2004 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2004

Arch Dermatol. 2004;140(11):1393-1398. doi:10.1001/archderm.140.11.1393-b

Hematoxylin-eosin staining of the biopsy specimen revealed a papillated, thickened, and markedly pigmented epidermis with an increased number of mature sebaceous lobules of various sizes and shapes in the reticular dermis. The side of the biopsy specimen corresponding to the area of clinical change contained a cystlike space marked by papillations lined by 2 layers of cells, the luminal side of which revealed decapitation secretion consistent with apocrine differentiation. Within the fronds of stroma created by the papillations is an infiltrate of plasma cells.