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December 2004

Topical Tacrolimus: An Effective Therapy for Zoon Balanitis

Arch Dermatol. 2004;140(12):1538-1539. doi:10.1001/archderm.140.12.1538

Plasma cell balanitis, or Zoon balanitis (ZB), is a chronic, benign, inflammatory process usually involving the glans penis and the prepuce. Different treatments have been attempted with partial success.1

Topical formulations of the immunosuppressant macrolide tacrolimus have proved effective in atopic dermatitis, but the use of topical tacrolimus in other skin diseases has only been partially explored.2-4 We report 3 cases of ZB treated with tacrolimus ointment.