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February 1920


Arch Derm Syphilol. 1920;1(2):200. doi:10.1001/archderm.1920.02350020085010

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To the Editor:—  I have read with interest Dr. Lester Hollander's article on "Urticaria Probably Due to Syphilis," which appeared in the January number of the Archives. The author says that "in the present literature no pruriginous lesions have as yet been attributed to syphilis." I would refer him to two valuable contributions by Hazen, one published in The Journal of the American Medical Association67:1650, 1916; the other in The American Journal of Syphilis1:750, 1917. Reference to the complication may also be found in Hazen: Syphilis, The C. V. Mosby Co., St. Louis, 1919, p. 155. In a series of 100 cases, Hazen found the Wassermann reaction positive in 33 per cent., and in every instance antisyphilitic treatment was followed by the disappearance of the urticaria. During the past two years, I have made it a point to subject every case of persistent urticaria to a