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July 1920


Author Affiliations

Associate Professor and Head of Division of Dermatology and Syphilology, University of Minnesota; Instructor in Dermatology and Syphilology, University of Minnesota MINNEAPOLIS

Arch Derm Syphilol. 1920;2(1):61-66. doi:10.1001/archderm.1920.02350070066009

Our attention was first called to the subject of lowered alkalinity in seborrheic eruptions by the article of Barber and Semon1 published in 1918. In a series of observations on soldiers in the British army, who had seborrheic eruptions, they found a pronounced and remarkably constant hyperacidity of the urine. This led them to the assumption that the seborrheic state is really a manifestation of relative acidosis. When the possibility of the existence of acidosis occurred to them, they began to test the therapeutic effects of giving alkali mixtures and making local applications of alkalies. Beneficial results were immediately apparent. From their clinical and chemical (urine) examinations, they considered that they had established these two fundamental facts:

  1. That the majority of patients with seborrheic manifestations show a markedly increased alkaline tolerance, many of them to an astounding degree.

  2. That in nearly all cases all active inflammatory processes