In a paper by Wile and Kingery, presented at the last annual meeting of the American Dermatological Society, were detailed a series of experiments directed toward a demonstration of the etiologic agent of molluscum contagiosum. As a result of their studies, these authors were able to show that the lesions of this disease can be produced experimentally from the sterile filtrate of molluscum lesions, thereby justifying their conclusion that molluscum contagiosum is caused by a filterable virus. The technic of these experiments, as carried out on themselves and their assistants, was comparatively simple. Molluscum lesions were removed by curettement, ground up in a mortar containing a small amount of sterile saline, and the resultant mash passed through the finest Berkefeld filter under negative pressure. The filtrate thus obtained, which produced no growth on all ordinary culture mediums, was injected intracutaneously into human subjects, at the points of predilection for the
KINGERY LB. THE HISTOGENESIS OF MOLLUSCUM CONTAGIOSUM. Arch Derm Syphilol. 1920;2(2):144–162. doi:10.1001/archderm.1920.02350080012002
Browse and subscribe to JAMA Network podcasts!
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: