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August 1920


Author Affiliations

Assistant Professor in Dermatology and Syphilology, University of Michigan Medical School ANN ARBOR, MICH.

Arch Derm Syphilol. 1920;2(2):144-162. doi:10.1001/archderm.1920.02350080012002

In a paper by Wile and Kingery, presented at the last annual meeting of the American Dermatological Society, were detailed a series of experiments directed toward a demonstration of the etiologic agent of molluscum contagiosum. As a result of their studies, these authors were able to show that the lesions of this disease can be produced experimentally from the sterile filtrate of molluscum lesions, thereby justifying their conclusion that molluscum contagiosum is caused by a filterable virus. The technic of these experiments, as carried out on themselves and their assistants, was comparatively simple. Molluscum lesions were removed by curettement, ground up in a mortar containing a small amount of sterile saline, and the resultant mash passed through the finest Berkefeld filter under negative pressure. The filtrate thus obtained, which produced no growth on all ordinary culture mediums, was injected intracutaneously into human subjects, at the points of predilection for the

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