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Article
November 1920

LYMPHOGRANULOMATOSIS OF THE SKIN IN HODGKIN'S DISEASE

Author Affiliations

NEW YORK

From the United States Public Health Service.

Arch Derm Syphilol. 1920;2(5):578-593. doi:10.1001/archderm.1920.02350110049003
Abstract

The cutaneous manifestations of Hodgkin's disease may in general be divided into two classes. The first of these includes a group of dermatoses not characteristic of Hodgkin's disease either clinically or histologically. In this class should be mentioned generalized prurigolike eruptions, pruritus, urticarial, hemorrhagic and bullous eruptions, pigmenation and universal exfoliative erythrodermias. In addition, certain disturbances of nutrition, such as alopecia areata, have been noted. Whether these manifestations are due to the toxic action of the (supposed) infectious agent in Hodgkin's disease, it is not my purpose to discuss. That the prurigo-like eruptions are not characteristic of this disease has been shown by microscopic examinations by Bowen1 and others. In a woman with typical Hodgkin's disease, Bowen noted prurigo-like lesions on the leg, one of which was examined histologically. He wrote, "It seems to me most rational to regard them as akin to the nodules of true prurigo, as

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