In a recent paper dealing with certain cutaneous manifestations of anaphylaxis, a well known writer1 states that "the cutaneous phenomena which occur as a result of the absorption of foreign proteins through the respiratory tract and possibly through the skin itself have not received the attention and study that they deserve." This statement, combined with a recent illuminating experience of my own, has prompted the presentation of this brief paper on a phase of this subject which is, I believe, of definite clinical interest, namely, that the skin alone, and even limited areas of the skin, may be sensitized by and react to direct contact with specific substances contained in the epidermal structures of certain animals, as shown in the following case report.
REPORT OF A CASE
Mrs. R., aged 39, an office assistant, came under observation Feb. 2, 1919, presenting a skin eruption of six months' duration,
MARKLEY AJ. ANAPHYLACTOID DERMATITIS DUE TO DIRECT CONTACT WITH ANIMAL EPIDERMAL STRUCTURES. Arch Derm Syphilol. 1920;2(6):722–724. doi:10.1001/archderm.1920.02350120050007
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