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Article
April 1921

PATHOLOGY OF RHUS DERMATITIS

Author Affiliations

WASHINGTON, D. C.

Arch Derm Syphilol. 1921;3(4_PART_1):383-403. doi:10.1001/archderm.1921.02350160038004
Abstract

DEFINITION  Rhus dermatitis caused by Rhus diversiloba and Rhus toxicodendron is an irritation of the skin caused, in the case of Rhus toxicodendron, by Pfaff's toxicodendrol and in the case of Rhus diversiloba by lobinol, a nonvolatile substance containing a polyhydrophenol with unsaturated side chains.1 These toxic substances may or may not have the same chemical composition.

ETIOLOGY  I have shown in preceding papers2 that the active principle lobinol is neither bacterial nor volatile, and that poisoning occurs from actual contact with the resinous sap of the plant. This contact, however, may result through an intermediary agent, which carries the sap, such as particles of soot in smoke, clothing, cordwood, croquet balls and shoes.

AVENUES CF INFECTION  A suitable channel must be present so that the pathogenic lobinol may enter the body and produce its specific disease. Such avenues of infection are the cutaneous surfaces, the respiratory, alimentary

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