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Society Transactions
April 1921


Arch Derm Syphilol. 1921;3(4_PART_1):445-446. doi:10.1001/archderm.1921.02350160100011

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SILVER SALVARSAN IN THE TREATMENT OF SYPHILIS. Drs. Covisa and Bejarano.  We have treated forty patients, including patients with primary, secondary and tertiary syphilis and neurosyphilis. Besides its action on the Wassermann test, silver arsphenamin causes these three remarkable effects on primary syphilis: (1) quick disappearance of the chancrous induration, (2) disappearance of spirochetes with 10 cg. of the drug, (3) quicker clearing of local adenopathies. In secondary and tertiary cases silver arsphenamin acts energetically and quickly in surprisingly small doses.The action of this drug on the Wassermann test has been discussed by German authors. As representative of the results obtained by us, we may mention two cases of serum positive primary syphilis and four cases of secondary syphilis. In the first two cases the Wassermann test became negative with 70 cg. and 40 cg. of silver arsphenamin, respectively. In the secondary cases the reaction became negative with doses

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