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Chatterji has collected information regarding the protean manifestations of syphilis from many authorities, and has amplified it from his own practice. His experience taught him that the manifestations which the disease undergoes in the tropics provide a great field for research. He believes that it is generally admitted that in the tropics (he speaks for India), syphilis manifests itself more in the lesions of the skin, mucous membranes, and in ulcers (tropical ulcers) than in typical tertiary lesions or parasyphilitic conditions. It has been suggested that various skin lesions, described under the name of tropical phagedenia or tropical ulcer, are really manifestations of syphilis. It is generally accepted that tertiary ulceration in the tropics assumes a malignancy which is not so common in cold climates. Many of the tropical conditions are of protozoal origin, for example, yaws, gangosa, and dermal leishmaniasis (oriental sore), and as such they may give positive