Practically ever since the discovery of the Wassermann1 reaction, investigators have endeavored to devise some simpler test which would give equally satisfactory results, and which, besides being of practical importance, might throw some light on the mechanism of the Wassermann reaction. Most of them have endeavored to accomplish this by various precipitation methods. The theory that the formation of a precipitate occurs in a positive Wassermann reaction was formulated by Michaelis,2 Levaditi and Yamanouchi,3 Elias, Neubauer, Porges and Salomon,4 and by Liefmann.5
In 1907, Fornet and Schereschewsky6 obtained what they believed to be specific precipitates by using the serums of patients with active syphilis as precipitinogen and the serums of patients with paresis as precipitin; they also used saline extracts of syphilitic livers as precipitinogen, but, while they obtained precipitates with these, they also obtained them by using normal liver extracts. In the same
PARKER F, HAIGH AVR. THE SACHS—GEORGI TEST FOR SYPHILIS. Arch Derm Syphilol. 1921;4(1):67–74. doi:10.1001/archderm.1921.02350200070007
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