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December 1921


Author Affiliations

Clinical Professor of Syphilology, Medical School of Harvard University; Chief of Department of Syphilis, Massachusetts General Hospital BOSTON

Arch Derm Syphilol. 1921;4(6):723-736. doi:10.1001/archderm.1921.02350250002001

In the treatment of early acquired syphilis we have to deal with two unequal groups. The larger is made up of the physically fit, the smaller consists of individuals with damaged organs, arteries or tissues, due to age or to disease.

Such may be the condition when syphilis is acquired. It is necessary, therefore, as soon as the diagnosis has been made to ascertain by thorough physical examination in which group the patient belongs. This division is more essential today than formerly, for we now aim at a radical cure in early cases. This means the use of more potent remedies than of old. The synthetic drugs which are supposedly parasitotropic may be organotropic as well, and the toxic effect of mercury on the tubules of the kidney is well known. These conditions play an important part in the management and care of all, but especially of the physically unfit.

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