Since my original publication,1 much interest has arisen as to the value of these fatty acids in leprosy and other diseases, especially tuberculosis.
On reviewing the literature on the use of the oil by subcutaneous injections, I find that it was probably first used by Blanc of New Orleans as early as 1888, according to Dyer.2
Sandes3 has also used it hypodermically at Robbins Island. Black4 gave a mixture of olive oil and chaulmoogra oil.
Ohmann-Dumesnil5 gives preference to the hypodermic administration of the oil.
Jeanselme,6 in 1911, published the formula which was probably the basis of the Mercardo formula employed later in the Philippines. It was composed of chaulmoogra oil, guaiacol and camphor.
Tourtoulis7 read a paper before the Academy of Medicine of Paris on several years' experience in the use of the oil subcutaneously.
Miguel8 and Unna9 both report
HOLLMANN HT. THE FATTY ACIDS OF CHAULMOOGRA OIL IN THE TREATMENT OF LEPROSY AND OTHER DISEASES. Arch Derm Syphilol. 1922;5(1):94–101. doi:10.1001/archderm.1922.02350260097010
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: