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Since the first edition of Nonne's book on "Syphilis and the Nervous System," which appeared in 1901, this popular text has gone through three editions, and grown from a book of about 400 odd pages to almost 1,000 pages of text.
The fourth edition contains added chapters dealing particularly with the treatment, the accidents due to arsphenamin, with particular reference to the effect on the nervous system, the various methods of intraspinal medication, vaccines, and the surgical treatment of spinal syphilis. As in previous editions, the book is rich in case histories illustrative of the various conditions under discussion, and additional illustrations, more or less diagrammatic to be sure, have been added.
Notwithstanding the author's apology in his preface for his inability to secure references from foreign countries during the late war, one cannot fail to be impressed by the tremendous knowledge of the literature and the extent to which