To one who has done cultural work on both the Blastomyces and the Hyphomycetes it is easy to understand how isolated elements of the one may resemble those of the other. But when it comes to dermatologic examinations of scrapings, pus, etc.—tissue products in general—we have been in the habit of believing that the Blastomyces should appear as round cells unassociated with mycelia, more or less, and vice versa for the Hyphomycetes. This still holds good as a general rule, and may turn out to be an absolute one when we come to know more about the genuineness of the pathogenicity of these higher fungi.
I have already cited an instance (illustrated) in which the scrapings from a case of ringworm of the nails showed bodies resembling Blastomyces,1 and in which the bodies were reproduced later by Penicillium brevicaule which was isolated in the cultures. Here a Hyphomycetes produced
WEIDMAN FD. RESEMBLANCE OF YEASTS IN CUTANEOUS SCRAPINGS TO HYPHOMYCETES. Arch Derm Syphilol. 1922;5(3):325–328. doi:10.1001/archderm.1922.02350280030003
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