The intravenous administration of mercuric chlorid is a comparatively recent method of treatment. Osler gives it passing mention in the eighth edition of "Principles and Practice of Medicine" (1914) under the subject "Treatment of Syphilis." Bavellie1 of Rome began using it in 1917 and claimed to have had excellent results. Within more recent years mercurial salts have been advocated for intravenous injections by Spittel2 of England, Sanz3 of Spain, Bastron4 of Lincoln, Neb., and Brocq.5 J. C. Klecan6 states that mercury can and should be given intravenously, his mode of administration being perfectly painless and safe. The results are prompt, from both the symptomatic and the serologic point of view. The patient is saved time and money, and the period of mental anguish is decidedly shortened.
By intravenous treatment Gutmann obtained 74 per cent. negative results; Zimmermann, 68 per cent.; Linser, 70 per cent.,
CONRAD AH, McCANN CH. XXVI.—RESULTS IN THE TREATMENT OF WASSERMANN-FAST SYPHILIS BY INTRAVENOUS MERCURIC CHLORID. Arch Derm Syphilol. 1922;6(1):50–54. doi:10.1001/archderm.1922.02360010053008
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