It was early in 1918, while the late Dr. W. S. Gottheil instructed a class of students at the Lebanon Hospital Dispensary, that a patient who had extremely foul smelling eczematoid lesions on and between the toes of both his feet, was presented to him for demonstration. He refused to show the patient to the students and advised a potassium permanganate dressing in order to do away with the foul odor. When the patient returned to the clinic three days after the dressing was applied, the results appeared startling. Not only had the foul odor disappeared, but the lesions had cleared up also to a great extent. The case was subsequently diagnosed as eczematoid ringworm, Epidermophyton inguinale being found in the scrapings of the lesions. Desirous of ascertaining whether the drug had any special action on the lesions or whether improvement was coincidental, the treatment was continued until the case
FELDMAN S, OCHS BF. POTASSIUM PERMANGANATE AS A CURATIVE AGENT IN DERMATOLOGIC DISEASES. Arch Derm Syphilol. 1922;6(2):163–166. doi:10.1001/archderm.1922.02360020036004
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