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Article
May 1923

CLINICAL NOTE ON LEUKODERMA ACQUISITUM CENTRIFUGUM (SUTTON)

Author Affiliations

ROCHESTER, MINN.

From the Section on Dermatology and Syphilology, Mayo Clinic.

Arch Derm Syphilol. 1923;7(5):611-618. doi:10.1001/archderm.1923.02360110040007
Abstract

In November, 1916, Sutton1 reported two cases of a peculiar form of depigmentation to which he gave the name leukoderma acquisitum centrifugum. This modification of vitiligo consisted in an oval or circular depigmented lesion, having at its center "a minute rounded, slightly elevated brownish maculopapule which resembled a small pigmentary nevus, which the patient said had been present only since the onset of the attack. The hyperpigmented areola commonly found in vitiligo was absent. The lesion had developed slowly and has never given rise to subjective symptoms of any kind." On histologic examination, Sutton believed that he recognized a collection of endothelial cells in the derma, which he interpreted as an infiltration. Treatment for one year was without effect.

Sutton's report aroused my interest, and during the last six years I have been on the lookout for similar cases with a view to defining more sharply the histologic and

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