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July 1923


Arch Derm Syphilol. 1923;8(1):19-30. doi:10.1001/archderm.1923.02360130022002

In October, 1920, Frederick S. Burns1 presented a study of xanthoma from the biochemical standpoint, in which he reached the conclusion that these interesting tumors are due to a high percentage of cholesterin in the blood and the subsequent deposit of cholesterin compounds in the tissues. His paper presented also a complete review of the literature, and his results were confirmatory of the work done by previous investigators.

The cases which we have studied in the past few years present also a uniformly high cholesterinemia, and we, therefore, put them on record. We present here the records of three cases of xanthoma diabeticorum and three cases of xanthoma tuberosum.


Case 1.—  Xanthoma diabeticorum. A white American, aged 29, was admitted to Barnes Hospital on Sept. 17, 1918. He was a waiter and his complaint was general weakness and a skin eruption. His family history was unimportant;

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