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Article
August 1923

ETIOLOGY AND PATHOGENIC RELATION BETWEEN CERTAIN DERMATOSES AND LEUKEMIA

Arch Derm Syphilol. 1923;8(2):319. doi:10.1001/archderm.1923.02360140156010

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Abstract

The author includes under the heading of leukemic states: leukemia, chloroma, lymphogranulomatosis, lymphosarcomatosis, leukemia cutis and mycosis fungoides. The first four are the result of a hyperplastic activity of the hematopoietic tissues, and the last two are due to the hyperplasia of the diffuse hematopoietic system of the subcutaneous tissue. The cutaneous manifestations accompanying the leukemias may be divided into three groups: leukemids, exfoliative erythrodermias and tumors. The leukemids are "the pruriginous exanthems which may appear in the course of the diffuse form of leukemia and which may or may not have themselves a leukemic structure" (Audry). The leukemids are: simple pruritus, prurigo, urticaria, purpura and pigmentation.

The exfoliative erythrodermias may be localized or generalized. The generalized form may be divided into primitive and secondary. The primitive forms are the acute and subacute dermatitis exfoliativa (Wilson-Brocq), the dermatitis exfoliativa chronica (Brocq) and the pityriasis rubra (Hebra).

The tumors are nodular

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