In May, 1922, my associates and I presented before the American Dermatological Association the results of a preliminary study on the experimental aspects of iodid and bromid exanthems. In the preliminary report1 it was shown that the ingestion of bromid readily displaced the chlorid in the blood; that apparently the kidney, readily filtering through both chlorid and iodid, reacted differently to the salts of bromin. These tend to be stored up after their ingestion, owing to the difficulty of their filtrability through the kidney epithelium. The constant ingestion and gradual storing up in the body of bromid (small amounts being eliminated through the bowel) leads to the clinical phenomena known as bromism.
The most striking manifestations of bromism are its effects on the central nervous system and on the skin. It was shown in our previous communication that no trace of bromid can be found in the local lesions
WILE UJ. FURTHER CONTRIBUTIONS TO THE EXPERIMENTAL ASPECTS OF IODID AND BROMID EXANTHEMS. Arch Derm Syphilol. 1923;8(3):407–410. doi:10.1001/archderm.1923.02360150084008
Artificial Intelligence Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.