Angiomas of the cavernous type usually create anxiety, especially when increasing in size, and they are usually so situated as to be disfiguring. The physician may find it difficult to exclude malignancy when the nevus is in a rare situation, or when its appearance is altered by necrosis.
After the continuous appearance of only girl babies with tuberous angiomas became apparent, with each new one the question, "Is it another girl baby?" became almost a joke. A one sex series of fourteen instances of girl babies with cavernous nevi was broken by the fifteenth case, and of eight subsequent instances only one was a male. The proportion of twenty-one females to two males, more than ten to one, would make interesting statistics were the number sufficiently large. No positive conclusion can be drawn from so small a number.
Previous to this series of cases presenting this type of nevi, those
CULVER GD. A SERIES OF ANGIOMAS IN BABIES. Arch Derm Syphilol. 1923;8(6):769–775. doi:10.1001/archderm.1923.02360180025003
Artificial Intelligence Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.