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March 1924


Author Affiliations

Associate in Section on Dermatology and Syphilology, Mayo Clinic ROCHESTER, MINNESOTA

Arch Derm Syphilol. 1924;9(3):293-304. doi:10.1001/archderm.1924.02360210002001

The dermatologic aspect of rat-bite fever apparently has been given little attention in the current literature of dermatology. Although the condition is not common, and a small proportion of the patients may not present cutaneous manifestations, the value of the cutaneous lesions as an aid to diagnosis is, in the majority of cases, about as great as in pellagra or early syphilis. It has been considered worth while, therefore, to discuss the literature briefly, and to report the findings in two cases observed in the Mayo Clinic since October, 1916: one of undoubted rat-bite fever, and one in which the diagnosis is presumptive.

Rat-bite fever was probably first reported by the French in 1884.1 It was not, however, until 1899 that Miyake2 reported it more in detail. In 1910, Horder3 mentioned the first cases noted in the literature of Great Britain, and since that time about 140

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