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Article
March 1924

LABORATORY DIAGNOSIS OF SYPHILIS. A MANUAL FOR STUDENTS AND PHYSICIANS

Arch Derm Syphilol. 1924;9(3):414. doi:10.1001/archderm.1924.02360210123013

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Abstract

The laboratory tests for syphilis are divided into those which detect Spirochaeta pallida and those which demonstrate changes in the body consequent to infection. Taking up first the complement-fixation reaction as the most important of the latter class, the first five chapters contain an excellent discussion of the phenomena on which the serum test is based. Then follow a description of the many modifications of the original Wassermann test, a chapter on the effect of inactivation of human serum and a full description of the technic of the author's modification of the test. The modifications using human complement are discussed and a preferred technic given. This is followed by a brief description of the Wassermann system and its modifications.

The author presents well and briefly the diagnostic value of the complementfixation test. The next chapter on the effect of antisyphilitic treatment on the serum test is evidently based on work

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