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June 1924


Arch Derm Syphilol. 1924;9(6):803-807. doi:10.1001/archderm.1924.02360240130011

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Neurofibroma. Presented by Dr. Wertheimer.  A woman, aged 21, had presented the condition for the past fifteen years. There were for the most part pea-sized, freely movable, hard tumors situated in the subcutaneous tissue occurring on the palmar and lateral surfaces of the joints of the fingers, palms, left thenar eminence, dorsal wrists (here resembling ganglia), extensor elbows, over the crests of the ilia, on the knees, insteps and heels. In places such as the wrists they appeared to be attached to the tendon sheath and on the arm as though attached to the veins. The skin over the tumors was normal. The patient complained of the tumors being sensitive to touch and having neuralgic pains at times. Roentgen-ray examination of the hands was negative. There was no connection between the joints and the tumors. The bones were normal.

DISCUSSION  Dr. Hollander said he could not make a definite diagnosis

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