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The introduction explains this as a second edition of Bruck's work on serodiagnosis; but as the first edition was published in 1909, the present work, considering the immense expansion of the literature of the complement-binding reaction and the many new tests devised since then, is more accurately a new book. The introductory chapter dealing with the history of the research which led up to the discovery of the reaction is of great interest, especially the statement giving Neisser credit for making the first suggestion that the complement-binding reaction should be applied to Syphilis. The chapter ends with the statement that "The most important factor in the reliability of the Wassermann-Neisser-Bruck reaction is always the sense of responsibility, the accuracy and trustworthiness of the technician." Bruck writes on the theoretic and experimental basis for the test and then discusses its specificity and diagnostic value. J. Zeissler writes on the technic, favoring
HANDBUCH DER SERODIAGNOSE DER SYPHILIS. Arch Derm Syphilol. 1924;9(6):808. doi:10.1001/archderm.1924.02360240135012
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