The cutaneous reaction brought about by the tubercle bacillus is polymorphous. While this polymorphy is not as great as that found in syphilis, nevertheless, there is an apparent analogy. In syphilis the examination for the spirochete, the Wassermann reaction and the response to antisyphilitic therapy are determining factors. Unfortunately, in tuberculosis the bacillus can be recovered only with difficulty, and there is no particular diagnostic test and no specific therapy. These factors make the problem of cutaneous tuberculosis a difficult one.
Cutaneous tuberculosis is divided into two main classes. First, true tuberculosis of the skin, which includes those forms in which the tubercle bacillus has been demonstrated with certainty, and, second, the so-called tuberculids or toxicodermas of suspected tuberculous origin. Fortunately, the tuberculid group is becoming smaller and smaller, and as more consistent positive findings are registered, certain clinical forms will be definitely recognized as true tuberculosis, and their origin
MICHELSON HE. SCROFULODERMA GUMMOSA (TUBERCULOSIS COLLIQUATIVA). Arch Derm Syphilol. 1924;10(5):565–578. doi:https://doi.org/10.1001/archderm.1924.02360290030006
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