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Article
November 1924

THE WASSERMANN TEST: XII. THE EFFECT OF INTRAMUSCULAR INJECTION OF NEO

Author Affiliations

BOSTON

From the Evans Memorial and Boston University School of Medicine.

Arch Derm Syphilol. 1924;10(5):601-606. doi:10.1001/archderm.1924.02360290066008
Abstract

This paper deals with the results of neo-arsphenamin used intramuscularly. It is the third of a series of papers that discuss the effect of certain antisyphilitic remedies on the Wassermann reaction. A freshly prepared 3 to 6 per cent, solution of neo-arsphenamin (Metz), pH value about 7.4, was injected into the gluteal muscles according to the Rosen-Fordyce technic, which proved especially satisfactory in the younger children, whose activity was difficult to control. A uniform dose of 0.0132 mg. per kilogram of body weight, equivalent to the maximum dose of 0.9 mg. for a 68 kg. patient, was administered in a course of six injections over a period of five weeks. The strength of the Wassermann reaction was measured as described in a previous paper,1 before treatment, at the third week and at one and four weeks

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